A Male Case of Primary Antiphospholipid Syndrome and Recurrent Deep Venous Thrombosis

Abstract

Antiphospholipid syndrome (APS) is an autoimmune disease with autoantibodies and hypercoagulability. Although APS has a variable clinical presentation, APS commonly presents vascular thrombosis and obstetrical complications, such as repeated miscarriages in women. Here, we report an elderly male with the clinical manifestations of APS and recurrent deep venous thrombosis (referred to as DVT) in Sudan. A 52 year-old male had a chief complaint of severe left leg pain and high-grade fever for 10 days, with no history of recent surgery, trauma or prolonged immobilization but with a previous history of DVT. Doppler ultrasonography revealed left lower limb DVT, and laboratory examinations detected autoantibodies without other causes. Accordingly, he was diagnosed with APS. He was treated with Cefuroxime, Flucloxacillin and subcutaneous enoxaparin. His clinical condition markedly improved and the swelling subsided. His blood international normalized ratio reached 2.5 and he was discharged.