A low-power low-noise multi-stage transimpedance amplifier for amperometric based blood glucose monitoring systems

Abstract

In this paper, the design of low-noise, low-power transimpedance amplifier (TIA) is presented for a miniaturized amperometric based continuous blood glucose monitoring system for wearable devices. The proposed multi-stage cascode common source transimpedance amplifier circuit is designed and implemented in a 180 nm CMOS technology. It has been demonstrated that the proposed TIA shows a significant increase in transimpedance gain, 1.72 GΩ with a bandwidth of 180 kHz and input referred current noise is 18 fA/√Hz for an input current of 200 pA. The total power consumption is 52 μW with a 1.4 V supply and occupies a chip area of 110 μm × 140 μm.