Abstract

Continuous respiratory monitoring is an important tool for clinical monitoring. Associated with the development of biomedical technology, it has become more and more important, especially in the measuring of gas flow and CO concentration, which can reflect the status of the patient. In this paper, a new type of biomedical device is presented, which uses low-power sensors with a piezoresistive silicon differential pressure sensor to measure gas flow and with a pyroelectric sensor to measure CO concentration simultaneously. For the portability of the biomedical device, the sensors and low-power measurement circuits are integrated together, and the airway tube also needs to be miniaturized. Circuits are designed to ensure the stability of the power source and to filter out the existing noise. Modulation technology is used to eliminate the fluctuations at the trough of the waveform of the CO concentration signal. Statistical analysis with the coefficient of variation was performed to find out the optimal driving voltage of the pressure transducer. Through targeted experiments, the biomedical device showed a high accuracy, with a measuring precision of 0.23 mmHg, and it worked continuously and stably, thus realizing the real-time monitoring of the status of patients.

Highlights

  • With the development of biosensor technology, biomedical devices have been widely developed for health monitoring, and health monitoring, especially respiratory monitoring, which mainly includes gas flow and CO2 concentration, has been increasingly emphasized [1]

  • In the wake of the development of biomedicine, biomedical sensor technology and computer science, biomedical devices have been widely used in health monitoring

  • As a significant tool in clinical monitoring, biomedical devices for respiratory monitoring have been of more concern with respect to researchers and patients

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Summary

Introduction

With the development of biosensor technology, biomedical devices have been widely developed for health monitoring, and health monitoring, especially respiratory monitoring, which mainly includes gas flow and CO2 concentration, has been increasingly emphasized [1]. Society of Anesthesiologists (ASA) [2], and gas flow monitoring provides more valuable information about patients and accurately delivers tidal volumes to a critically sick patient [3]. In most previous works, few studies focused on the monitoring of the gas flow and CO2 concentration simultaneously [8,9,10]. There exist some difficulties, including size limits, the requirement for monitors to work continuously for a long time and the requirement for a stable power source. It is urgent to use small portable and stable biomedical device that can be attached to the patient for clinical applications [11,12,13,14,15]

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