Abstract
For patients with chronic obstructive pulmonary disease (COPD) at risk for exacerbation, the 2016 Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines recommend either the combination of a long-acting β-agonist (LABA) plus an inhaled glucocorticoid (ICS) or monotherapy with a long-acting muscarinic antagonist (LAMA). Although some studies have shown that ICS use is associated with fewer exacerbations (especially in patients with eosinophilia …
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