Abstract
A team of scientists led by Professor DW Pang at Wuhan University have developed a new class of fluorescence probes based on bacterial cells. These microbial factories manufacture semiconductor nanocrystals inside and display protein A molecules on cell surface, transforming Staphylococcus aureus (S. aureus) cells into highly fluorescent cellular beacons that can be easily adapted for detection of diverse biological targets.
Highlights
A team of scientists led by Professor DW Pang at Wuhan University have developed a new class of fluorescence probes based on bacterial cells
Fluorescent and monodisperse quantum dots (QDs) are often chemically synthesized via high-temperature organometallic procedure [5]
Coupling yeasts’ natural intracellular metabolic reaction of Na2SeO3 and detoxification of Cd ions, highly fluorescent CdSe QDs can be made with precisely controlled sizes and emission wavelengths
Summary
A team of scientists led by Professor DW Pang at Wuhan University have developed a new class of fluorescence probes based on bacterial cells. Fluorescent and monodisperse QDs are often chemically synthesized via high-temperature organometallic procedure [5]. Dr Pang’s group at Wuhan University, China, has developed a very interesting approach by taming yeast cells into a living QD synthesizer [6]. Coupling yeasts’ natural intracellular metabolic reaction of Na2SeO3 and detoxification of Cd ions, highly fluorescent CdSe QDs can be made with precisely controlled sizes and emission wavelengths.
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