Abstract
Patients with atopic dermatitis suffer from skin barrier defects and recurrent skin infections due to filaggrin (FLG) deficiency and reduced antimicrobial peptide expression. Anecdotal reports suggest that plant extracts from Chamaecyparis Obtusa have beneficial effects on skin health. However, it has not been reported whether they modulate FLG and human beta defensin (HBD)-3. Therefore, we investigated whether a lipid plant extract from Chamaecyparis Obtusa induces FLG and HBD-3.
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