Abstract
In this paper, a new organic-inorganic hybrid compound [Co(L)2]2 [W6O19](1) (HL = 2-acetylpyridine thiosemicarbazone) was prepared and characterized. The compound exhibits remarkable antibacterial activity by determination of minimum inhibitory concentration (MIC) against Staphylococcus aureus (S. aureus, 0.06 µg/mL) and Escherichia coli (E. coli, 0.24 µg/mL), respectively. Furthermore, the potential mechanism of 1 was studied in detail. The potential causes of bacteria death were cell wall/membrane disruption, inhibition of intracellular respiratory chain dehydrogenases activity (RCD), breach of reactive oxygen species (ROS) and glutathione (GSH).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
