Abstract

we have developed a numerical scheme based on the mesoscopic Lattice Boltzmann Method (LBM) to simulate the coarse-grained coupled reaction-diffusion equations model used to describe the MinD/MinE interaction in two dimensions. Biologically, we have focused on investigating how the protein copies affect the oscillation patterns as well as cell division. Interestingly, numerical solutions reveal that the oscillation pattern and some physical properties become altered considerably depending on “Min protein crowd”’. This finding may suggest that the failure in cell dividing may be due to being abnormal in protein regulations or expression to control Min protein copies. Good agreement between the experimental and numerical results is found and discussed.

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