Abstract

The rapid sensitive detection of biomolecules, microorganisms and cells is critical to human, animal, and plant health along with food and environmental safety. Available detection techniques such as enzyme-linked immunosorbent assays (ELISA) and polymerase chain reaction (PCR) have high sensitivity but require the acquisition of discrete samples and excessive lab personnel time. Recently a lateral field excited (LFE) sensor has been developed (1) which has a bare sensing surface allowing the measurement of both mechanical and electrical property changes in a target analyte selective film. In the present work the LFE sensor is evaluated as a biosensor using anti-rabbit IgG and Escherichia coli (E. coli) as target analytes. The LFE sensor properties are compared to those obtained using a QCM biosensor. I. INTRODUCTION

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