A Large Parathyroid Adenoma- A Textbook Case in Pathology

Enrique Vazquez Quintana

doi:10.4172/2476-2024.1000106

Abstract

My interest in parathyroid surgery was prompted by an assignment from Dr. Cuello Mainardi in 1964. He required that I conduct a seminar on the topic of hypercalcemia. For this purpose, I prepared a paper for the house staff on the differential diagnosis of hypercalcemia, which includes: sarcoidosis, milk-alkali syndrome, multiple myeloma, hypernephroma, metastatic bone disease, and hyperparathyroidism. The event was pivotal to what became a life-long career as a thyroid and parathyroid surgeon.

Highlights

In 1963, I entered my residency in General Surgery at the University of Puerto Rico and Affiliated Hospitals in San Juan, Puerto Rico
We have presented a patient with severe symptoms of hyperparathyroidism, markedly elevated calcium levels, bony cyst, nephrocalcinosis, and a large mediastinal adenoma
At the time of her operation, there were no localizing tests, nor the electric saw to open the sternum. This demonstrates that in the past, good results could be obtained with the tools that were available

Summary

Introduction

In 1963, I entered my residency in General Surgery at the University of Puerto Rico and Affiliated Hospitals in San Juan, Puerto Rico. In 1961, he removed the first parathyroid adenoma in Puerto Rico. My interest in parathyroid surgery was prompted by an assignment from Dr Cuello Mainardi in 1964. He required that I conduct a seminar on the topic of hypercalcemia. The patient remained asymptomatic until 1990, when she was found to have mild hypercalcemia Both the PTH-C terminal and the PTH intact tests were elevated as well. To this day, this is the second largest parathyroid adenoma ever reported in the medical literature. The following a table showing the parathyroid adenomas weighing over 50 grams reported in the medical literature. The patient was a 41-year-old female who presented anorexia, weight loss, polydipsia, polyuria, and constipation, bone pain in the pelvis, lacrimation, and burning sensation of the

Discussion

Summary