Abstract

The pustule of pustular psoriasis of Zumbusch type has been examined electron microscopically. A Langerhans cell was found in the pustule cavity and its cytoplasm contained granules closely similar in morphology to the distinctive granules of neutrophils. These granules were conglomerated and surrounded by a membrane as a whole. Other organelles of the cell were well preserved, indicating its active cellular function. On the other hand, organelles of keratinocytes around the pustule appeared to undergo degenerating processes. It is suggested that the Langerhans cell is capable of carrying out phagocytosis more actively than keratinocytes under some pathological condition.

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