Abstract
Herbal formulation dosage form consists of one or more herbs processed in specified quantities to provide specific nutritional, cosmetic benefits use to diagnose the disease. Herbal formulations contain an active substance and preparation in combination of one or more herbal compounds. Berberis aristata is one of herbs of an ancient Ayurveda medicine and different properties along with various treatment of illness. Berberine, is a type of alkaloid which is quarternary protoberberine, is one of the known bioactive compounds scattered extensively in a number of clinically significant medicinal plants such as Hydrastis canadensis L., Phellodendron amurense R. ,Coptis japonica M., and Berberine containing plants have been used in traditional and folk medicine around the globe for centuries. It has been used for a, anti-pyretic diarrhea, bitter tonic, and eye infections. In the past three eras, Berberine has been studied intensively in over thousands cases because of its therapeutics, physicochemical effects, pharmacological, and physiological effects such as cardiovascular, anti-inflammatory, anti leshmanial, and anti- secretory, effects. Berberine act as a phytoconstituents in formulations and available in ayurveda, allopathy, and homeopathy medicines. With this review, we will evaluate the various traditional and medicinal use of Berberine and their isolation and extraction procedure. We will also review the potential of this plant as various dosage forms for the treatment of various diseases.
 Keywords: Berberine; Extraction Method; Isolation method; Skin problems
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