Abstract
Twenty-four patients with chronic allergic rhinitis participated in a study of antihistamine effects on skilled performance. They were tested while experiencing symptoms and when they were free of symptoms. Within each symptom condition, they attended two sessions; each patient received a placebo capsule at one session and a 50 mg diphenhydramine capsule at the other. Subjects performed a battery of skilled performance tests, which included the Divided-Attention, Visual Backward Masking, Stimulus Response Conflict, and Vigilance tests. They rated the treatments and their performance. Affective states were assessed with the Profile of Mood States. Symptoms did not affect performance. Diphenhydramine impaired vigilance performance and measures of Divided Attention and Stimulus Response Conflict. Visual Backward Masking performance was not affected. The largest performance changes occurred when diphenhydramine was administered to subjects when they were free of symptoms.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
