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Abstract
This report describes an in vitro method which predicts the antimicrobial effects of the drugs which are used for topical application in the treatment of infected burn wounds. Standard in vitro disc sensitivities are not available for this panel of drugs. The test incorporates an evaluation of the drug carriers, creams and ointments, which are not factors in standard disc or dilution sensitivity methods. Quantitative bacteriological data following treatment of infected burn wounds in children support the conclusion that the in vitro test correctly selects effective antimicrobial agents.
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