Abstract
As an oral nonsteroidal antiestrogen drug, tamoxifen (TMX) has been widely utilized for the prevention and treatment of breast cancer. In the current research, using differential-pulse voltammetry (DPV), an electrochemical investigation of the interaction between TMX and salmon-sperm double-stranded DNA (ds-DNA) was conducted with a graphene paste electrode (GPE). To determine TMX, a simple and sensitive biosensor was fabricated through this interaction. A linear dynamic range between 8.0 × 10−7 and 8.5 × 10−5 M was exhibited by DPV for TMX. Finally this modified electrode was used for determination of TMX in TMX tablet, serum and urine samples.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
