Abstract

Introduction: Birth defects are structural or functional changes that occur during intrauterine life. The dentist must recognize the craniofacial defects, complement the phenotypic characterization and manage them within a multidisciplinary team. The present review aims to assist the dentist to diagnose these findings and present syndromic conditions typically associated with craniofacial malformations
 Literature Review: Craniofacial manifestations of birth defects are conditions that must be recognized by dentists, as they are frequently present in their daily practices, and this professional may be the first to identify such findings. The main syndromic clinical pictures typically associated with micrognathia, oral clefts and skeletal dysplasias with craniofacial manifestation are presented, pointing out their clinical and genetic features. Discussion: The dentist must perform a detailed anamnesis including family history, as well as should recognize both clinical and radiographically the dysmorphisms, observing the patient systemically. Conclusion: Dentistry professionals should receive theoretical-practical training for the diagnosis, treatment and surveillance of individuals with congenital defects, either in individual assessment or as part of a multiprofessional team.

Highlights

  • Birth defects are structural or functional changes that occur during intrauterine life

  • The present review aims to assist the dentist to diagnose these findings and present syndromic conditions typically associated with craniofacial malformations

  • Literature Review: Craniofacial manifestations of birth defects are conditions that must be recognized by dentists, as they are frequently present in their daily practices, and this professional may be the first to identify such findings

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Summary

Introduction

Birth defects are structural or functional changes that occur during intrauterine life. Literature Review: Craniofacial manifestations of birth defects are conditions that must be recognized by dentists, as they are frequently present in their daily practices, and this professional may be the first to identify such findings. Na sequência de Pierre-Robin há um defeito primário do desenvolvimento da mandíbula, levando a uma mandíbula pequena (micrognatia) que ocasionará uma retração da língua (glossoptose) e disfunção respiratória, com ou sem fechamento inacabado do palato (fenda palatina). Síndrome é um conjunto de defeitos congênitas que se relacionam patofisiologicamente, entretanto não podem ser explicadas em uma sequência única (por exemplo, Síndrome de Patau)[3,10,11]. A maioria das malformações maiores ocorre como defeitos isolados, embora muitas vezes possam ser essenciais para atender aos critérios de diagnóstico de uma síndrome reconhecível. Tais conhecimentos são fundamentais ao dentista para o diagnóstico dessas condições e adequado encaminhamento do paciente a uma equipe multidisciplinar

Revisão de literatura
Fendas orais
Autossômica dominante e autossômica recessiva
Ligada ao X
Ligada ao X dominante
Autossômica recessiva
Displasias esqueléticas
Alterações dentárias
Conflito de interesses
Full Text
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