A hybrid of NiCo-PBNCs nano-composite supported two-dimensional molybdenum disulfide as excellent peroxidase mimics for colorimetric glucose detection

Abstract

The anchoring of two-dimensional nanosheets (2D) with Prussian blue nanocubes has exhibited the advantage of high electron conductivity and better catalytic application. Herein, we reported the successful fabrication of molybdenum disulfide-supported Prussian blue nanocubes (MoS2@NiCo-PBANCs) and compared the bare MoS2 and NiCo-PBNCs for effective peroxidase, such as catalytic activity, which can catalyze the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) by the generation of H2O2, ensuring the appearance of blue colored solution. The MoS2@NiCo-PBANCs exhibited an excellent colorimetric sensing performance toward glucose in urine samples. Therefore, the present method demonstrates the high sensitivity, selectivity, simplicity, and fast colorimetric sensing ability for H2O2 and glucose detection. The synergistic effect of MoS2@NiCo-PBNCs reveals lower detection limits of 0.0075 µM and 0.01 µM for H2O2 and glucose, respectively. The exclusive structural morphology, excellent stability, large surface area, and high catalytic property have been utilized to achieve the closer interaction of glucose oxidase and TMB with MoS2@NiCo-PBANCs to oxidize glucose to gluconic acid. Overall, we utilized the MoS2@NiCo-PBNCs as a novel composite nanomaterial for the application of H2O2 and glucose peroxidase-like mimics in the urine sample.