A Hybrid Data Mining Model to Predict Coronary Artery Disease Cases Using Non-Invasive Clinical Data.

Abstract

Coronary artery disease (CAD) is caused by atherosclerosis in coronary arteries and results in cardiac arrest and heart attack. For diagnosis of CAD, angiography is used which is a costly time consuming and highly technical invasive method. Researchers are, therefore, prompted for alternative methods such as machine learning algorithms that could use noninvasive clinical data for the disease diagnosis and assessing its severity. In this study, we present a novel hybrid method for CAD diagnosis, including risk factor identification using correlation based feature subset (CFS) selection with particle swam optimization (PSO) search method and K-means clustering algorithms. Supervised learning algorithms such as multi-layer perceptron (MLP), multinomial logistic regression (MLR), fuzzy unordered rule induction algorithm (FURIA) and C4.5 are then used to model CAD cases. We tested this approach on clinical data consisting of 26 features and 335 instances collected at the Department of Cardiology, Indira Gandhi Medical College, Shimla, India. MLR achieves highest prediction accuracy of 88.4%.We tested this approach on benchmarked Cleaveland heart disease data as well. In this case also, MLR, outperforms other techniques. Proposed hybridized model improves the accuracy of classification algorithms from 8.3% to 11.4% for the Cleaveland data. The proposed method is, therefore, a promising tool for identification of CAD patients with improved prediction accuracy.