Abstract

Swine are susceptible to the same influenza A virus subtypes as humans--H1N1, H3N2 and H1N2--and the histories of influenza in pigs and people are closely linked. Many swine influenza viruses are a result of reassortment and their genes are composed of human and avian and/or swine virus genes. Indeed, it is known that both human and avian influenza viruses occasionally transmit to pigs, and that pigs can serve as "mixing vessels" for these viruses, meaning that viruses can exchange genetic material and lead to the production of a new "hybrid" virus. This has led to the thinking that perhaps pandemic viruses could emerge following reassortment in pigs. However, since nobody has observed the start of a pandemic, there remains no direct evidence to make this more than a theory.

Highlights

  • Influenza is one of the major causes of acute respiratory disease in pigs, but subclinical infections are common

  • The viruses in Europe differ significantly in their antigenic and genetic make-up from those circulating in North America, even though they consist of the same H and N subtypes, and findings in the United States should not necessarily be extrapolated to Europe

  • Retrospective epidemiological investigations found no evidence of any further cases apart from the general practitioner (GP) who had experienced similar symptoms but was not laboratory-confirmed [5]

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Summary

Introduction

Influenza is one of the major causes of acute respiratory disease in pigs, but subclinical infections are common. The symptoms and pathogenesis of influenza in pigs show remarkable similarities with those of seasonal influenza in humans, but the epidemiology is different. Humans in contact with pigs occasionally become infected by swine influenza viruses [4].

Results
Conclusion

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