A Hospital Based Cross-Sectional Study to Evaluate Ovarian Cancer Risk after Salpingectomy

Abstract

Objective: The main objective of this hospital based cross-sectional study was to evaluate ovarian cancer risk after salpingectomy. Material and Methods: This hospital based cross-sectional observational study was carried out over a period of 1 year (Oct 2019 – Oct 2020) conducted at SS Hospital, Bihar. By descriptive statistics & Pearson Chi square test using SPSS software the collected data were analysed. Results: 257 patients were included in salpingectomy group, whereas 312 were under Hysterectomy and BSO group. Mean age at entry was 35.7± 8.9 years at Salpingectomy group whereas the same was 37.9 ±4.8 years with Hysterectomy and BSO group. When compared with the Hysterectomy and BSO population for ovarian cancer and among women with previous salpingectomy there was a statistically significantly lower risk observed. A further 50% decrease in risk of ovarian cancer was associated with Bilateral salpingectomy compared with the unilateral procedure (unilateral: HR = 0.73, 95% CI = 0.57 to 0.92; bilateral salpingectomy: HR = 0.36, 95% CI = 0.17 to 0.75). Conclusion: Reduced risk of ovarian cancer is associated with salpingectomy on benign indication. This data also in line with the concept that in the fallopian tube ovarian cancer arises at a substantial fraction. Our results suggest that in the general population to reduce ovarian cancer risk an effective measure is the removal of the fallopian tubes by itself.