Abstract
The brainstem location of afferent and efferent components in rat carotid sinus nerve (CSN) was determined by transecting the CSN and applying horseradish peroxidase. Afferent label was heaviest in the ipsilateral medial solitary nucleus (mNTS). Afferents were also found in the ipsilateral ventrolateral solitary nucleus, area postrema, and bilaterally in the commissural nucleus of the solitary complex. Efferent labeled cells were found in the ipsilateral rostral nucleus ambiguus and the inferior salivatory nucleus. The CSN afferents in the mNTS terminated rostral to neurons which project to the nucleus ambiguus thus implicating the existence of interneurons in the baroreceptor reflex pathway.
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