A histological study of the Harderian gland of Mongolian gerbils, Meriones meridianus.

Abstract

The histological structure of the gerbil Harderian gland was investigated by means of light and transmission electron microscopy. The single excretory duct of the gland is directly continuous with endpieces at the hilus and opens nasally and ventrally to the third eyelid. The excretory duct is accompanied by many acini of small serous glands around it. The gland is composed of tubuloalveoli (tubular alveoli) with wide lumina and is not divided into lobules. There is no branched duct system within the gland. The tubuloalveoli themselves convey the secretory materials to the hilus where the excretory duct begins. The alveolar epithelium is composed of only one type of glandular cell as well as myoepithelial cells. The glandular cells contain many clear secretory vacuoles containing lipids and well-developed tubular smooth endoplasmic reticulum. The secretory vacuoles are surrounded by a unit membrane and are secreted by exocytosis. The interstices of the gland contain two types of autonomic nerve varicosities and a number of melanocytes. The surface of the gland is covered with the endothelium of the orbital venous sinus.