Abstract

The amounts fo ribonucleic acid and glycogen-containing granules increased in the cytoplasm of epithelial cells during inflammatory proliferation of the cutaneous epithelium of the rabbit ear. Differentiation of the hyperplastic epithelial cells was accompanied by an increased intensity of the tetrazolium coupling reaction, as well as by increased reactions for sulphydril and carboxylic groups. The invasive growth of the epithelium was associated with destruction of the basement membrane, or with the accumulation of chromotropic mucopolysaccharides near the epithelial outgrowths.

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