Abstract
A new reaction-based, colorimetric fluorescent sensor of BODIPY derivative (1) for cysteine (Cys) has been designd and synthesized. This probe shows highly selective detection of Cys over homocysteine (Hcy), glutathione (GSH) as well as other amino acids with a dramatic color change from wine red to fluorescence green because of the significant increase of the visible light excitable fluorescence intensity with the addition of Cys, due to their different reaction rates of the Michael addition reaction. The detection limit for Cys was 8.57×10−7M. Possible mechanism for sensing of Cys by BODIPY 1 was studied by NMR and HRMS. Probe 1 has been successfully applied to the biological imaging of Cys in living cells.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
