Abstract
The fixed bed ion exchange column was proven to be an efficient method in the simultaneous fermentation and separation process for various organic acids, and was used in my work to explore fumaric acid production process. The adsorption and desorption processes were investigated using D201 resin in the column. NaHCO3 was selected as optimal stripping agent and the desorption percentage reached 97.01%. The HCO3− exchanged by fumaric acidcould be recycled back to the stirred-tank reactor and consumed as neutralizer without the influence on the adsorption of the next batch. When the optimum conditions were utilized in the simultaneous fermentation and separation process, 17.53 g/L of fumaric acid with 0.21 g/L h of volumetric productivity were obtained without extra neutralizers supplied. The results indicated that it was an efficient in-situ separation system and had a potential utilization in industrialized production of fumaric acid.
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