Abstract

A novel concept of a low-pressure single gradient mixing pump is described. The solvents are mixed via a two-way switching valve of special design. Due to a mechanical transmission between the pump piston and the gradient valve rotor, the precise partitioning of the both liquids is achieved regardless of a nonlinear piston refill period. The use of this concept has no limitations for specially constructed pumps equipped with stepping motors and with position encoders for piston displacement. For isocratic elution with mixed solvents it is possible to set manually any binary composition without the need of any additional accessory.

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