Abstract

Nail involvement by pemphigus vulgaris is uncommon and has been associated with the severity of disease. Paronychia, onychomadesis, Beau's lines, nail hemorrhages, cross riding, discoloration, hyperkeratosis, pitting, pterygium, onychodystrophy, onycholysis, onychorrhexis, onychoschizia and trachyonychia have been reported. These nail disorders may appear before, concomitantly or after the typical manifestations of pemphigus flare ups. Two adult patients presenting with nail disorders associated with pemphigus vulgaris are herein commented. Case studies might contribute to enhance the awareness about these nail disturbances very scarcely reported.

Highlights

  • Nail involvement by pemphigus vulgaris is uncommon and has been associated with the severity of disease

  • Paronychia, onychomadesis and onycholysis are nail changes more often found in patients with Pemphigus Vulgaris (PV), but these lesions are only rarely indicative of the bullous condition [1]

  • I have read with interest the recent case study by Zawar, et al describing recurrent paronychia, which appeared in all fingers and four toes of an Indian woman before her diagnosis of Pemphigus Vulgaris (PV) [2]

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Summary

Introduction

Nail involvement by pemphigus vulgaris is uncommon and has been associated with the severity of disease. These nail disorders may appear before, concomitantly or after the typical manifestations of pemphigus flare ups. Two adult patients presenting with nail disorders associated with pemphigus vulgaris are commented.

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Conclusion
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