Abstract

A sensitive separable-type detection method based on giant magnetoimpedance effect in NiFe/Cu/NiFe/Cu/Cr films for detecting traces of magnetic beads (4.5 μm) at high frequency (> 5 MHz) was presented in this paper. A microcavity with a basement thickness of 0.3 mm was fabricated by Micro-nano carving technology, and was immobilized on the meander-shaped sensing elements for loading Dynabeads. Large resistance variations were observed in the frequency range of 30 MHz∼120 MHz by the presence of Dynabeads. This method is able to detect Dynabeads as low as 10 particles using one single giant magnetoimpedance sensor without external magnetic fields and redundant washing steps, demonstrating high sensitivity, low complexity and nondestructive characteristic.

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