Abstract

This paper proposes a machine learning approach dealing with genetic programming to build classifiers through logical rule induction. In this context, we define and test a set of mutation operators across from different clinical datasets to improve the performance of the proposal for each dataset. The use of genetic programming for rule induction has generated interesting results in machine learning problems. Hence, genetic programming represents a flexible and powerful evolutionary technique for automatic generation of classifiers. Since logical rules disclose knowledge from the analyzed data, we use such knowledge to interpret the results and filter the most important features from clinical data as a process of knowledge discovery. The ultimate goal of this proposal is to provide the experts in the data domain with prior knowledge (as a guide) about the structure of the data and the rules found for each class, especially to track dichotomies and inequality. The results reached by our proposal on the involved datasets have been very promising when used in classification tasks and compared with other methods.

Highlights

  • Current data management and storage methods have been challenged by the high increase in the amount of medical data available to us

  • This section describes the experiments carried out by our proposal on the clinical datasets, which have been selected from Machine Learning Repository [62]

  • This work has proposed a machine learning method focused on genetic programming to render rule-based classifiers

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Summary

Introduction

Current data management and storage methods have been challenged by the high increase in the amount of medical data available to us. GAs have been applied to different fields in medicine, among which we can highlight, Radiology, Oncology, Cardiology, Endocrinology, Pulmonology and Pediatrics, among others In this context, GAs have been used for edge detection of images obtained from Magnetic Resonance Imaging (MRI), Compute Tomography (CT) and ultrasound [27,28,29]. GAs have been used for edge detection of images obtained from Magnetic Resonance Imaging (MRI), Compute Tomography (CT) and ultrasound [27,28,29] Making use of these kinds of algorithms, different methods have been proposed to detect microcalcifications in mammograms leading to diagnosing breast cancer [30,31,32]. The designed algorithm can detect lung nodules with about 86% sensitivity, 98% specificity, and 97.5% accuracy

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