Abstract
A tool that analyzes the genome of parasites found in the blood of malaria patients can help inform policy decisions on how best to tackle the rise in drug-resistant infections.
Highlights
Malaria cases may have decreased over the last 15 years, but the number of parasites resistant to treatment is rising, in Southeast Asia
The reduced susceptibility to artemisinin and its partner drugs has resulted in artemisinin-based combination therapy (ACT) therapy failing to treat over 50% of malaria cases in some regions of Cambodia, Thailand and Vietnam
Jacob et al collaborated with various National Malaria Control Programs and scientific partners to collect 9,623 blood samples from patients diagnosed with P. falciparum malaria in eight countries (Vietnam, Laos, Cambodia, Thailand, Myanmar, Bangladesh, India and Democratic Republic of Congo)
Summary
Malaria cases may have decreased over the last 15 years, but the number of parasites resistant to treatment is rising, in Southeast Asia. The reduced susceptibility to artemisinin and its partner drugs has resulted in ACT therapy failing to treat over 50% of malaria cases in some regions of Cambodia, Thailand and Vietnam (van der Pluijm et al, 2020; van der Pluijm et al, 2019). Jacob et al collaborated with various National Malaria Control Programs and scientific partners to collect 9,623 blood samples from patients diagnosed with P. falciparum malaria in eight countries (Vietnam, Laos, Cambodia, Thailand, Myanmar, Bangladesh, India and Democratic Republic of Congo).
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