Abstract
Summary - The effect of ethyl methane sulfonate-induced mutations in different germ cell stages on male reproductive fitness at early and late age, compared to an untreated control, was investigated in a laboratory population of Drosophila melanogaster. Indication of active DNA repair processes after mutagen treatment was obtained in the pre-meiotic germ cell stages. Genetic parameters for the male fitness trait, ie number of were estimated in a succession of different broods at early and late ages. Heritability estimates for progeny size were found to vary between 0.13 and 0.97 in the different brood stages and over the 2 treatment groups. The estimates of genotype-environment interaction, as well as genetic correlations, suggest that the genetic determination of progeny size is different at an early age between EMS-treated and untreated individuals, but not at late ages.
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