Abstract

The application of machine learning and artificial intelligence techniques in the medical world is growing, with a range of purposes: from the identification and prediction of possible diseases to patient monitoring and clinical decision support systems. Furthermore, the widespread use of remote monitoring medical devices, under the umbrella of the “Internet of Medical Things” (IoMT), has simplified the retrieval of patient information as they allow continuous monitoring and direct access to data by healthcare providers. However, due to possible issues in real-world settings, such as loss of connectivity, irregular use, misuse, or poor adherence to a monitoring program, the data collected might not be sufficient to implement accurate algorithms. For this reason, data augmentation techniques can be used to create synthetic datasets sufficiently large to train machine learning models. In this work, we apply the concept of generative adversarial networks (GANs) to perform a data augmentation from patient data obtained through IoMT sensors for Chronic Obstructive Pulmonary Disease (COPD) monitoring. We also apply an explainable AI algorithm to demonstrate the accuracy of the synthetic data by comparing it to the real data recorded by the sensors. The results obtained demonstrate how synthetic datasets created through a well-structured GAN are comparable with a real dataset, as validated by a novel approach based on machine learning.

Highlights

  • Chronic Obstructive Pulmonary Disease (COPD) is a critical pulmonary disease affecting about 5–10% of the adult population [1] and is associated with significant healthcare and socioeconomic burden; it is important to carefully prevent and monitor such disease

  • We propose a new implementation for remote monitoring through Pneulytics, a platform to monitor and manage patients with COPD [5]

  • That means Fréchet Inception Distance (FID) may anticipate the quality of XAI, avoiding the need for its continuous testing over all the candidate data augmentation runs

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Summary

Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a critical pulmonary disease affecting about 5–10% of the adult population [1] and is associated with significant healthcare and socioeconomic burden; it is important to carefully prevent and monitor such disease. Remote monitoring of diseases and treatments is based on the collection of vital parameters (such as heart rate, blood oxygenation, sleep and activity of the patient) necessary to evaluate possible immediate and timely medical interventions to avoid worsening of the disease and related clinically relevant symptoms and, in general terms, to improve the quality of life of patients, their families and the population [2,3,4]. Within this umbrella, we propose a new implementation for remote monitoring through Pneulytics, a platform to monitor and manage patients with COPD [5]. The platform is able to collect clinical data from IoMT devices to analyze such data using artificial intelligence (AI) algorithms

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