A Generational Study on Vitmamin D Status of Selected Type 2 Diabetics

Abstract

Introduction: There is a rising surge of T2DM and hypo-vitaminosis D among Indians. The main role of vitamin D in bone metabolism is to increase the plasma levels of calcium and phosphorus, essential for mineralization. Mineralization is a passive process, but it only occurs when calcium and vitamin D are available in sufficient quantities. Vitamin D plays important roles in the metabolism of glucose. It directly stimulates insulin secretion from beta cells of pancreas. It increases intracellular calcium levels which attenuates insulin synthesis. Method: Therefore, we aimed to study the vitamin D status and bone health between diabetic and non-diabetic off-springs (GII & GIII) of the selected diabetics (GI). We conducted a cross-sectional study over three generations to assess their vitamin D status and bone health. The tools included the online vitamin D estimator and serum vitamin D levels. Results: The correlation study shows that the parameters of the VDDRS are positively correlated to serum Vitamin D levels. However, the degree to which they were positively correlated varies greatly. Day frequency and dense fabric clothing were very strongly correlated. The serum VD levels of the diabetic and non-diabetics GII participants were significantly different both among the males and females (p≤0.05). Conclusion: Since vitamin D has such a vast role in health particularly in the case of T2DM, we recommend that VDDRS may use in routine screening and assessment of T2DM for appropriate treatment.