Abstract
A simple and efficient Gas Chromatography GC analysis method was developed to identify and quantify plasticizers commonly used with polymers present in delayed release tablets The plasticizers investigated included Dibutyl Sebacate DBS Tributyl Phosphate TBP and Tributyl Acetyl Citrate TBAC The Gas Chromatography GC analysis method employs a common DB GC column mx micro m micro m film The method was shown to be specific and linear r Both accuracy and precision were established across the analytical range mg mL Method applicability was demonstrated by analyzing currently marketed DR tablets from different manufacturers
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