Abstract

Licence to Kill: A β-galactosidase-responsive molecular “Trojan horse” was designed to selectively kill folate receptor-positive tumor cells. The recognition of the folate membrane receptor is followed by the internalization and the subsequent enzymatic activation of the targeting assembly to release the cytotoxic agent in a stringently controlled fashion exclusively inside the targeted cells. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

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