Abstract
INTRODUCTIONIN EARLIER work it was observed that vitamin B12 supplementation of deficient basal diets led to reduced blood levels of certain free amino acids. The chicks given vitamin B12, with lower blood levels of these amino acids grew faster, and made more efficient utilization of their feed than did the controls. This finding led to the provisional hypothesis that vitamin B12 enhances anabolic utilization of amino acids in the chick (Charkey et al., 1950); confirmed by Menge and Combs (1950). The present paper reports a further study in which that hypothesis has been put to more comprehensive test. EXPERIMENTALPlan of Experiment. It was desired first of all to repeat, in essence, the earlier work in which effects had been observed on an ad libitum feeding basis. These effects had not been large, however, and it was thought that they might be increased by resampling all treatments after putting …
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