Abstract
This paper proposed a fully integrated 4-channel GMR biochip for biomedical detection assays, including the acquisition analog frontend for small signal extraction, 180° phase shifter, resistor ladder and control circuits for carrier cancellation, and amplifiers. Besides, the overall system was evaluated comprehensively by experiment, and the output noise is as low as $$321.7\mathrm {nV/\sqrt{Hz}},$$ which is lower than the signal produced by one single 500nm magnetic particle during the detection.
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