Abstract
Abstract Research showed that the normothermic machine perfusion of kidneys can enable prolonged storage and improve conditions compared to traditional cold storage. For research in this area, there is a demand for a long-term in vitro perfusion setup. In this work, we present a fully automated normothermic machine perfusion (NMP) system as an experimental research platform. The perfusion system is intended as a tool for researching the effects of different perfusion strategies on the kidney. To enable the automation, the NMP system consists of a blood pressure control, a circulation volume level control and a pH-regulation component. The setup is realized as a medical cyber-physical system consisting of networked embedded microcontroller nodes.
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