Abstract
The purpose of the study was to analyze results of 2-year follow-up of patients with idiopathic pulmonary fibrosis (IPF). Methods. Medical records of 83 patients admitted to the Pulmonology Department of the Territorial Teaching Hospital in 2013–2017 were analyzed retrospectively. Results. IPF patients were predominantly males (63.86%) over 50 years of age (90.37%). Two-year mortality rate was 26.5%. Died patients had significantly lower SpO2 and lung function (FVC and FEV1) and significantly higher serum C-reactive protein level at first admission compared to survived patients. Honeycomb lungs were seen at HRCT in 72.5% of died patients. In survived patients, SpO2 and 6-minute walk distance significantly decreased after 2 year of the follow-up. Proportion of patients with honeycomb lungs at HRCT increased from 20.8% to 75.0%. The diagnosis was revised in 8.4% of patients after 2 years of the follow-up. Conclusion. Patients with IPF should be referred to a multidisciplinary center as soon as possible in order to confirm the diagnosis, to be included in the register and to be regularly followed.
Highlights
Целью настоящего исследования явился анализ 2-летнего динамического наблюдения пациентов с Идиопатический легочный фиброз (ИЛФ), госпитализированных в 2013–2017 гг. в пульмонологическое отделение Государственного бюджетного учреждения здравоохранения «Научноисследовательский институт – краевая клиническая больница No 1 им
Change in dyspnea severity measured by mMRC scale in patients with idiopathic pulmonary fibrosis у 100 % пациентов, у > 50 % отмечена одышка III–IV степени по шкале одышки Modified Medical Research Council
Вместе с тем согласно полученным в работе данным, у больных Идиопатический легочный фиброз (ИЛФ) наиболее частым сопутствующим заболеванием была ишемическая болезнь сердца (22,5 %), что, возможно, обусловлено более старшим возрастом пациентов; доля лиц с гастроэзофагеальная рефлюксная болезнь (ГЭРБ) составила только 15,2 %
Summary
Е.В.Болотова 1, 2, Л.В.Шульженко 1, 2, В.А.Порханов 1, 2, И.Н.Райбова 1, Н.И.Макрушина 1. – Федеральное государственное бюджетное образовательное учреждение высшего образования «Кубанский государственный медицинский университет Минздрава России»: 350065, Краснодар, ул. – Государственное бюджетное учреждение здравоохранения «Научно-исследовательский институт – краевая клиническая больница No 1 им.
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