Abstract
Traditional surgical treatment of chronic rhinosinusitis with nasal polyps is not always definitive since a high rate of polyps recurrenceis reported all over the world Precision medicine with the utilization of biological therapies could be a new opportunity for accurately selected patients with nasal polyp rsquo s regrowth that underwent previous surgery In this review we provide a brief historiography of the surgical treatments of chronic rhinosinusitis with without nasal polyps and describe the first applications of biological therapies
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