A Fluorinated Supramolecular Self‐Assembled Peptide as Nanovaccine Adjuvant for Enhanced Cancer Vaccine Therapy (Small Methods 5/2023)

Abstract

Front Cover In article number 2201409, Daqing Sun, Dan Ding, and co-workers propose a fluorinated supramolecular strategy for developing a cancer vaccine adjuvant, of which 4RDP(F5) containing tetra-arginine (4R) and dipentafluorophenylalanine (DP(F5)) balances the self-assembly, antigen affinity, and transmembrane abilities. The performance of 4RDP(F5)-OVA in prevention and treatment of tumors makes it an attractive vaccine adjuvant candidate in cancer immunotherapy.