Abstract
A fluorimetric analytical method using test strips has been fabricated for detecting Hg2+ ions in blood by using copper nanoclusters (Cu NCs) prepared via a biomineralization route. Unexpectedly, the as-prepared Cu NCs displayed greatly amplified red fluorescence once dispersed in DMSO, the intensity of which decreased specifically in the presence of Hg2+. Moreover, the resultant Cu NCs were deposited onto test strips to be further fast dried on superhydrophobic substrates in vacuum. The test strip-based fluorimetry can allow for the direct analysis of Hg2+ in blood in the linear concentration range of 0.10-1000 nM. Importantly, this solvent-enhanced fluorescence protocol for different metal probes such as Cu NCs promises extensive analysis applications for designing numerous fluorimetric platforms such as test strips.
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