Abstract
This review navigates the evolving landscape of Type 2 Diabetes (T2D) management by examining recent advancements in medication therapy, spanning from conventional approaches to groundbreaking innovations. Recognizing the dynamic nature of diabetes treatment, we delve into the traditional antidiabetic agents, such as metformin and sulfonylureas, and evaluate their sustained relevance in the context of contemporary therapeutic regimens. The synthesis of established treatments with novel pharmacological interventions takes center stage as we explore the transformative impact of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and sodium-glucose co-transporter-2 inhibitors (SGLT-2Is). These agents not only address glycemic control but also demonstrate cardiovascular and renal benefits, reshaping the paradigm of T2D management. Additionally, we investigate promising emerging therapies, including dual and triple combination therapies, personalized medicine approaches, and the potential role of oral hypoglycemic drugs in optimizing treatment strategies. By embracing a fluid and integrative perspective, this review aims to provide healthcare professionals and researchers with a comprehensive understanding of the diverse pharmacotherapeutic options available, fostering informed decision-making and paving the way for enhanced personalized care in the dynamic landscape of T2D management
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