Abstract
Despite its ubiquitous geographic distribution, the domestic mouse has not received attention from the cytogenetic point of view in South America, possibly because of its apparently conservative karyotype. In this paper we report, for the first time outside the Old World, a polymorphism for a Homogeneously Staining Region (HSR) between G-bands C5 and D of chromosome 1 in commensal populations of house mice from Misiones and Corrientes provinces (Argentina). The HSR is of the Mus musculus domesticus type as has been previously described for European populations. The comparison at the cytogenetic and molecular levels of chromosome polymorphisms such as the one described in this paper, between Old and New World house mice can help clarify the origin and antiquity of New World populations.
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