Abstract

Electrical impedance myography is a transcutaneous neuromodulation method for assessing muscle conditions through the application of a high-frequency, low-intensity current to the muscle region of interest (ROI). It has been shown that the mechanisms underpinning these findings are controversial as studies showed that the current reaching the target structure may not be enough to activate tissue due to various factors. It has been shown that anatomical properties as well as non-anatomical factors including electrode shape and size, inter-electrode distance may affect the outcome. This study was conducted to investigate the impact of the different sizes of the electrodes on the current density of the ROI. It may not be feasible to investigate these parameters impact on the outcome using experimental procedures. Alternatively, the computational methos have been used as a tool to study electrical stimulation of bio-computational models. The neuromodulators can be designed and developed using such advanced methods. This study investigates the impact of the electrode size on the current distributions. The fundamental anatomical layers of the human forearm were generated based on standard dimensions using concentric shapes. A sinusoidal bipolar current pulse was applied on the different sizes of electrodes to simulate current distribution within the associated anatomical layers. It was shown that the electrode size has a significant impact on the induced current density of the target anatomical layer.

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