Abstract

Modern radiotherapy techniques involve routine use of volumetric arc therapy (VMAT) and intensity modulated radiotherapy (IMRT) with jaw‐tracking – dynamic motion of the secondary collimators (jaws) in tandem with multi‐leaf collimators (MLCs). These modalities require accurate dose calculations for the purposes of treatment planning and dose verification. Monte Carlo (MC) methods for radiotherapy dose calculation are widely accepted as capable of achieving high accuracy. This paper presents an efficiency‐enhancement method for secondary collimator modeling, presented in the context of a tool for MC‐based dose second checks. The model constitutes an accuracy trade‐off in the source model for the sake of efficiency enhancement, but maintains the advantages of MC transport in patient heterogeneities. The secondary collimator model is called Flat‐Absorbing‐Jaw‐Tracking (FAJT). Transmission through and scatter from the secondary collimators is neglected, and jaws are modeled as perfectly absorbing planes. To couple the motion of secondary collimators with MLCs for jaw‐tracking, the FAJT model was built into the VCU‐MLC model. Gamma‐index analysis of the dose distributions from FAJT against the full BEAMnrc MC simulations showed over 99% pass rate for a range of open fields, two clinical IMRT, and one VMAT treatment plan, for 2%/2 mm criteria above 10%. Using FAJT, the simulation speed of the secondary collimators for open fields increased by a factor of 237, 1489, and 1395 for 4 × 4, 10 × 10, and 30 × 30 cm2, respectively. In general, clinically oriented simulation times are reduced from “hours” to “minutes” on identical hardware. Results for nine representative clinical cases (seven with jaw‐tracking) are presented. The average 2%/2 mm γ‐test success rate above the 80% isodose was 96.8% when tested against the EPIDose electronic portal image‐based dose reconstruction method and 97.3% against the Eclipse analytical anisotropic algorithm.

Highlights

  • Dose calculations in radiation therapy have been performed by algorithms of varying complexity and accuracy with calculations based on Monte Carlo (MC) methods being arguably the most accurate in complex geometries and heterogeneous media encountered in clinical dosimetry and treatment planning.[1,2,3,4,5,6,7,8]

  • In the clinical verification plans that were compared with EPIDose reconstruction and analytical anisotropic algorithm (AAA) calculations, c-index pass rates in

  • The FAJT model was shown to provide a substantial reduction in simulation times at the cost of a small accuracy sacrifice

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Summary

Introduction

Dose calculations in radiation therapy have been performed by algorithms of varying complexity and accuracy with calculations based on Monte Carlo (MC) methods being arguably the most accurate in complex geometries and heterogeneous media encountered in clinical dosimetry and treatment planning.[1,2,3,4,5,6,7,8] For this reason, MC techniques are expected to play a substantial role in radiotherapy treatment dose calculations and verification in the foreseeable future. Complete MC simulations of the linear accelerator head and patient geometry can be computationally expensive and require calculation times prohibitively long for use during the treatment planning and dose verification stages. Modern generations of fast dose calculation codes employ advanced variance reduction techniques to dramatically improve dose calculation efficiency in the phantom – this leaves treatment head modeling as the computational bottleneck. Many strategies for fast source models involve the use of phase-space files.[9,10,11,12,13]

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