Abstract

This article introduces a fast and plug-and-play mechanical connector for microfluidic chips. With this connection device, fast and pluggable connection between microfluidic chips and liquid storage tanks can be achieved, allowing microfluidic flow between the storage tank and the chip and between chips while ensuring airtightness and avoiding liquid leakage. The reason for liquid leakage and the maximum sealing pressure are theoretically analyzed from the perspective of surface tension. The relationship between different liquids (surface tension coefficient), air gap distance, and leakage pressure is explored. Furthermore, the effect of fast connection method and capillary connection method on liquid flow inside the chip is compared. The experiment shows that the flow rate using the fast connection method can reach at least 70% of that using the capillary connection method, and can gradually increase to 96% with increasing pressure and flow rate.

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