Abstract
Reductive amination of aromatic aldehydes using NaBH4 and isoxazole amines is carried out in a Brønsted acidic ionic liquid 1-methylimidazolium tetrafluoroborate [(HMIm)BF4]. The ionic liquid plays dual roles of solvent as well as catalyst for the efficient transformation of aromatic aldehydes to heterocyclic substituted amines in excellent yields without any undesired side product formation. The newly synthesized compounds (3, 6 and 7) were characterized by IR, 1H NMR and mass spectral techniques.
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