Abstract
AbstractThe one‐step synthesis of 8‐t‐butoxycarbonyl‐6,7‐dimethyl‐2‐oxo‐1,2,3,4‐tetrahydropyrrolo[1,2‐a]pyrimidine from acetyl methyl carbinol, 3‐aminopropionic acid, and t‐butyl cyanoacetate is reported. Utilizing a similar technology under basic conditions, 7‐substituted 5,6‐dimethyl‐2‐oxo‐2,3‐dihydro‐(1H)‐pyrrolo[1,2‐a]imidazole is synthesized from acetyl methyl carbinol, ethyl glycinate, and the appropriate acetonitrile.
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