A facile synthesis of 2-aryl-4-(indol-3-yl)-4H-chromenes using amberlyst-15 as an efficient recyclable heterogeneous catalyst

Abstract

Starting from 2-hydroxychalcones and indoles, a facile synthesis of 2-aryl-4-(indol-3-yl)-4H-chromenes has been achieved by use of amberlyst-15, a sulfonated polystyrene resin, as a recyclable heterogeneous catalyst. The methodology involves a domino sequence of Michael addition, cyclization, and dehydration.